Job de Lange Selected Research

Neoplasms (Cancer)

1/2020	WAPL-Dependent Repair of Damaged DNA Replication Forks Underlies Oncogene-Induced Loss of Sister Chromatid Cohesion.
10/2015	Defective sister chromatid cohesion is synthetically lethal with impaired APC/C function.
8/2012	MDM4 is a key therapeutic target in cutaneous melanoma.
9/2011	Oncogenic functions of hMDMX in in vitro transformation of primary human fibroblasts and embryonic retinoblasts.

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Job de Lange Research Topics

Disease

4	Neoplasms (Cancer) 01/2020 - 09/2011
1	Aneuploidy (Aneuploid) 01/2022
1	Melanoma (Melanoma, Malignant) 08/2012
1	Carcinogenesis 08/2012
1	Retinoblastoma (Glioblastoma, Retinal) 09/2011

Drug/Important Bio-Agent (IBA)

2	Proteins (Proteins, Gene)FDA Link 08/2012 - 09/2011
1	Phosphotransferases (Kinase)IBA 01/2022
1	CohesinsIBA 01/2020
1	apcinIBA 10/2015
1	PoisonsIBA 10/2015
1	Paclitaxel (Taxol)FDA LinkGeneric 10/2015
1	Carrier Proteins (Binding Protein)IBA 08/2012
1	nutlin 3IBA 09/2011

Therapy/Procedure

1	Drug Therapy (Chemotherapy) 08/2012
1	Therapeutics 08/2012